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Article

Bridging sequence diversity and tissue-specific expression by DNA methylation in genes of the mouse prolactin superfamily.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2012

Hayakawa Koji, Nakanishi Momo O, Ohgane Jun, Tanaka Satoshi, Hirosawa Mitsuko, Soares Michael J, Yagi Shintaro, Shiota Kunio

Abstract excerpt

Much of the DNA in genomes is organized within gene families and hierarchies of gene superfamilies. DNA methylation is the main epigenetic event involved in gene silencing and genome stability. In the present study, we analyzed the DNA methylation status of the prolactin (PRL) superfamily to obtain insight into its tissue-specific expression and the evolution of its sequence diversity. The PRL superfamily in mice...

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Identifiers

PMID: 22193412
DOI: 10.1007/s00335-011-9383-x
PMCID: PMC4834219

Genes

PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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