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MeDIP-seq and RNA-seq analysis during porcine testis development reveals functional DMR at the promoter of LDHC

27 Aug 2022

Abstract excerpt

Testis development requires tight regulation of gene expression programmed by epigenetic modifiers. However, their mechanism remains to be elucidated. Here, we investigated the genome-wide DNA methylation landscape in the Duroc and Meishan boar testes using methylated DNA immunoprecipitation sequencing (MeDIP-seq). We identified over 1100 promoter differential methylation genes (DMGs) before and after puberty,...

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PMID: 36041633
DOI: 10.1016/j.ygeno.2022.110467

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