Article
Common polymorphisms in the P-selectin gene in women with recurrent spontaneous abortions.
Gene - 1 Mar 2012
Dendana Maryam, Hizem Sondes, Magddoud Kalthoum, Messaoudi Safia, Zammiti Walid, Nouira Mona, Almawi Wassim Youssef, Mahjoub Touhami
Abstract excerpt
BACKGROUND: To investigate possible associations of P-selectin polymorphisms with idiopathic recurrent pregnancy loss (RPL). METHODS: Study subjects comprised 270 consecutive RPL cases attending outpatient maternity services, and 322 multi-parous control women. P-selectin genotyping was done by PCR-RFLP and PCR-ASA methods. RESULTS: The P-selectin variants rs1800807, rs1800805, and rs6127, were in Hardy Weinberg...
Read the complete abstract on PubMed