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Virus-Induced Tumorigenesis and IFN System

1 Oct 2021

Abstract excerpt

Oncogenic viruses favor the development of tumors in mammals by persistent infection and specific cellular pathways modifications by deregulating cell proliferation and inhibiting apoptosis. They counteract the cellular antiviral defense through viral proteins as well as specific cellular effectors involved in virus-induced tumorigenesis. Type I interferons (IFNs) are a family of cytokines critical not only for...

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PMID: 34681093
DOI: 10.3390/biology10100994

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