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Article

C9-R95X polymorphism in patients with neovascular age-related macular degeneration.

Investigative ophthalmology & visual science - 31 Jan 2012

Nishiguchi Koji M, Yasuma Tetsuhiro R, Tomida Daisuke, Nakamura Makoto, Ishikawa Kohei, Kikuchi Masato, Ohmi Yuhsuke, Niwa Toshimitsu, Hamajima Nobuyuki, Furukawa Koichi, Terasaki Hiroko

Abstract excerpt

PURPOSE: A non-sense mutation at codon 95 in the gene encoding complement factor C9 (C9-R95X) is found most frequently among Japanese. The authors investigated the association between C9-R95X and Japanese patients with neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV). METHODS: The presence of the C9-R95X polymorphism was assessed by direct sequencing in Japanese...

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Identifiers

PMID: 22190594
DOI: 10.1167/iovs.11-8425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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