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Article

Genetic analysis of complement factor H related 5, CFHR5, in patients with age-related macular degeneration.

Molecular vision - 1 Jan 2009

Narendra Umadevi, Pauer Gayle J T, Hagstrom Stephanie A

Abstract excerpt

PURPOSE: To investigate the complement factor H related 5 (CFHR5) gene, encoding a member of the complement factor H family, for the presence of genetic polymorphisms or mutations associated with age-related macular degeneration (AMD). METHODS: We screened 639 unrelated patients with AMD and 663 age-matched normal controls using direct genomic sequencing of the ten coding exons, along with the immediately...

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Source

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Identifiers

PMID: 19365580
PMCID: PMC2667568

Genes

CFHR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic analysis of complement factor H related 5, CFHR5, in patients with age-related macular degeneration.PMID 19365580Read ↗

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Hypothetical LOC387715 is a second major susceptibility gene for age-related macular degeneration, contributing independently of complement factor H to disease risk.Semantic proximity Read ↗

The Functional Effect of Rare Variants in Complement Genes on C3b Degradation in Patients With Age-Related Macular Degeneration.Semantic proximity Read ↗

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