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Article

Genotype-based changes in serum uric acid affect blood pressure.

Kidney international - 1 Mar 2012

Parsa Afshin, Brown Eric, Weir Matthew R, Fink Jeffrey C, Shuldiner Alan R, Mitchell Braxton D, McArdle Patrick F

Abstract excerpt

Elevated serum levels of uric acid consistently correlate with hypertension, but the directionality of the association remains debated. To help define this relationship, we used a controlled setting within a homogeneous Amish community and the Mendelian randomization of a nonsynonymous coding sin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22189840
DOI: 10.1038/ki.2011.414
PMCID: PMC3640827

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22189840-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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