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Article

Genetic analysis of C5a receptors in neutrophils from patients with familial Mediterranean fever.

Molecular biology reports - 1 May 2012

Apostolidou Eirini, Kambas Konstantinos, Chrysanthopoulou Akrivi, Kourtzelis Ioannis, Speletas Matthaios, Ritis Konstantinos, Mitroulis Ioannis

Abstract excerpt

Familial Mediterranean fever (FMF) is an autoinflammatory disease, characterized by MEFV gene mutations and self-limited recurrent episodes of fever and localized serositis. Complement system is a key regulator of the inflammatory process. The aim of this study was to investigate the genetic alterations and mRNA expression pattern of C5aR and C5L2 genes in neutrophils from attack-free FMF patients. No mutations...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22187344
DOI: 10.1007/s11033-011-1353-6

Genes

MEFV

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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