Article
Investigation of C5a receptor gene 450 C/T polymorphism in Turkish patients with familial Mediterranean fever.
Molecular biology reports - 1 Jan 2010
Erken Eren, Gunesacar Ramazan, Ozer Huseyin T E
Abstract excerpt
Familial Mediterranean fever (FMF) is a genetic disorder with acute inflammatory serosal attacks due to MEFV gene mutations which resides in chromosome 16. Lack of a C5a inhibitor activity in the peritoneum has previously been proposed in part to contribute in propagation of the serosal inflammation in FMF attacks. The aim of this study is to investigate C5a receptor (C5aR) gene polymorphism in patients with FMF...
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