Article
[Role of repair gene polymorphism in estimating the sensitivity of human genome to radon in concentrations exceeding maximum permissible level].
Gigiena i sanitariia - 1 Jan 2000
Druzhinin V G, Volkov A N, Glushkov A N, Golovina T A, Minina V I, Ingel' F I, Larionov A V, Meĭer A V, Lunina A A, Tolochko T A, Akhal'tseva L V, Krivtsova E K, Iurtseva N A, Iurchenko V V
Abstract excerpt
The paper gives the results of investigating chromosome aberrations in human peripheral blood lymphocytes due to DNA repair genes, such as hOGG1, ADPRT, APE1, XRCC1, XpG, XpC, XpD, and NBS1, upon long-term exposure to excess indoor radon concentrations. The frequency of chromosome aberrations was found to be significantly lower in the carriers of the genotype hOGG1 326 Ser/Ser (versus the variant Ser/Cys), APE1...
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