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Article

Significance of amino acid substitution variants of DNA repair genes in radiosusceptibility of cervical cancer patients; a pilot study.

Neoplasma - 1 Jan 2008

Farkasova T, Gurska S, Witkovsky V, Gabelova A

Abstract excerpt

The present pilot study was designed to elucidate the functional significance of amino acid substitution variants of DNA repair genes. Using the peripheral blood lymphocytes (PBLs) from healthy donors and cervical cancer patients, the contribution of four non-synonymous single nucleotide polymorphisms (SNPs) in three base excision repair genes (BER), XRCC1 (Arg194Trp and Arg399Gln), hOGG1 (Ser326Cys), and APE1...

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Share to DNA-(Apurinic or Apyrimidinic Site) Lyase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18505345

Genes

XRCC1
OGG1

Provenance

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Significance of amino acid substitution variants of DNA repair genes in radiosusceptibility of cervical cancer patients; a pilot study.PMID 18505345Read ↗

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