Article
[The evaluation of association between polymorphisms of DNA excision repair enzyme genes and risk of malignant tumors development in Siberian Group of Chemical Enterprises workers].
Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000
Freĭdin M B, Ivanina P V, Takhauov R M, Goncharova I A, Dvornichenko M V, Karpov A B
Abstract excerpt
There was analyzed single nucleotide polymorphisms of DNA excision repair enzyme genes hOGG, XPD, XPG, XRCC1 in 98 Siberian Group of Chemical Enterprises cancer patients and 148 healthy donors. No association was observed between the analyzed polymorphisms and malignant tumors in both control and subgroup (under study) of persons exposed to occupational ionizing radiation. Heterozygosis for the genes hOGG and XPD...
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