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Article

RNA-Binding Proteins in Cardiomyopathies

5 Mar 2024

Abstract excerpt

The post-transcriptional regulation of gene expression plays an important role in heart development and disease. Cardiac-specific alternative splicing, mediated by RNA-binding proteins, orchestrates the isoform switching of proteins that are essential for cardiomyocyte organization and contraction. Dysfunctions of RNA-binding proteins impair heart development and cause the main types of cardiomyopathies, which...

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PMID: 38535111
DOI: 10.3390/jcdd11030088

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