Article
AHI1 gene expression levels and BCR-ABL1 T315I mutations in chronic myeloid leukemia patients.
Hematology (Amsterdam, Netherlands) - 1 Nov 2011
Balci Tugce Bulakbasi, Sahin Feride Iffet, Karakus Sema, Ozdogu Hakan
Abstract excerpt
With the availability of molecular monitoring of BCR-ABL1 and the use of tyrosine kinase inhibitors, treatment in chronic myeloid leukemia (CML) is now molecularly focused. Eighty-three samples taken at different time points from 38 CML patients; were subjected to T315I mutation analysis and gene expression analysis of AHI1; a novel gene that is thought to have a role in both BCR-ABL1 mediated leukemic...
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