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Polymorphisms and haplotype of mitochondrial DNA D-loop region are associated with polycystic ovary syndrome in a Chinese population.

Mitochondrion - 1 Mar 2021

Deng Xiaohong, Ji Dongmei, Li Xinyuan, Xu Yuping, Cao Yu, Zou Weiwei, Liang Chunmei, Lee Marley Jordan, Zhang Zhiguo, Wei Zhaolian, Zhou Ping, Liu Yajing, Cao Yunxia

Abstract excerpt

Polymorphisms in mitochondrial DNA (mtDNA) have been linked to a range of diseases. Here we investigate the relationship between mtDNA D-loop region polymorphisms, mtDNA haplotype and polycystic ovary syndrome (PCOS), as well as the correlation of D-loop variants and clinical characteristics of PCOS, in a Chinese population. The mtDNA D-loop of whole blood samples from 421 PCOS patients and 409 controls underwent...

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PMID: 33385542
DOI: 10.1016/j.mito.2020.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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