Article
FOXE1 polyalanine tract length screening by MLPA in idiopathic premature ovarian failure.
Reproductive biology and endocrinology : RB&E - 16 Dec 2011
Qin Chun-rong, Yao Ji-long, Zhu Wen-jie, Wu Wei-qing, Xie Jian-sheng
Abstract excerpt
BACKGROUND: FOXE1 is one of the candidate genes for genetic predisposition to premature ovarian failure (POF) and it contains an alanine tract. Our purpose is to assess the influence of length of the alanine tract of FOXE1 on genetic susceptibility to POF. METHODS: The group studied consisted of 110 Chinese patients with idiopathic POF and 110 women from normal controls. The polyalanine tract and flanking...
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