Article
An investigation into FOXE1 polyalanine tract length in premature ovarian failure.
Molecular human reproduction - 1 Mar 2006
Watkins Wendy J, Harris Sarah E, Craven Megan J, Vincent Andrea L, Winship Ingrid M, Gersak Ksenija, Shelling Andrew N
Abstract excerpt
Premature ovarian failure (POF) is a common condition affecting 1% of women worldwide. There is strong evidence for genetic involvement in POF as many cases are familial, and mutations in several genes have been associated with POF. We investigated variation in FOXE1 polyalanine tract length, following the observation that polyalanine tract deletions are seen in the closely related FOXL2 in patients with POF. In...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
