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Article

Carboxyl/cholinesterases: a case study of the evolution of a successful multigene family.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Dec 1999

Oakeshott J G, Claudianos C, Russell R J, Robin G C

Abstract excerpt

The evolution of organismal diversity among the Metazoa is dependent on the proliferation of genes and diversification of functions in multigene families. Here we analyse these processes for one highly successful family, the carboxyl/cholinesterases. One key to the expansion of the functional niche of this group of enzymes is associated with versatile substrate binding and catalytic machinery. Qualitatively new...

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Identifiers

PMID: 10580988
DOI: 10.1002/(SICI)1521-1878(199912)22:1<1031::AID-BIES7>3.0.CO;2-J

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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