Article
Leukemic transformation in myeloproliferative neoplasms: therapy-related or unrelated?
Best practice & research. Clinical haematology - 1 Jun 2014
Björkholm Magnus, Hultcrantz Malin, Derolf Åsa Rangert
Abstract excerpt
Polycythemia vera, essential thrombocythemia, and primary myleofibrosis are chronic myeloproliferative neoplasms (MPNs) associated with an increased morbidity and mortality. MPNs are also associated with progression to acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). The "true" rate of transformation is not known mainly due to selection bias in clinical trials and underreporting in...
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