Article
Molecular pathways in sporadic PD.
Parkinsonism & related disorders - 1 Jan 2012
Valente Enza Maria, Arena Giuseppe, Torosantucci Liliana, Gelmetti Vania
Abstract excerpt
Over the last decade, several autosomal dominant and recessive genes causative of Parkinson's disease (PD) have been identified. The functional studies on their protein products and the pathogenetic effect related to their mutations have greatly contributed to understand the many cellular pathways leading to neurodegeneration, that include oxidative stress damage, mitochondrial dysfunction, misfolded protein...
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