Article
Molecular genetic pathways in Parkinson's disease: a review.
Clinical science (London, England : 1979) - 1 Oct 2005
Jain Shushant, Wood Nicholas W, Healy Daniel G
Abstract excerpt
Major progress has been made in the last decade in understanding the genetic basis of PD (Parkinson's disease) with five genes unequivocally associated with disease. As a result, multiple pathways have been implicated in the pathogenesis of PD, including proteasome impairment and mitochondrial dysfunction. Although Mendelian genetics has been successful in establishing a genetic predisposition for familial PD,...
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