Article
Human alveolar epithelial cell injury induced by cigarette smoke.
PloS one - 1 Jan 2011
Kosmider Beata, Messier Elise M, Chu Hong Wei, Mason Robert J
Abstract excerpt
BACKGROUND: Cigarette smoke (CS) is a highly complex mixture and many of its components are known carcinogens, mutagens, and other toxic substances. CS induces oxidative stress and cell death, and this cell toxicity plays a key role in the pathogenesis of several pulmonary diseases. METHODOLOGY/PRINCIPAL FINDINGS: We studied the effect of cigarette smoke extract (CSE) in human alveolar epithelial type I-like...
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