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Article

Global enhancement of nuclear localization-dependent nuclear transport in transformed cells.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Mar 2012

Kuusisto Henna V, Wagstaff Kylie M, Alvisi Gualtiero, Roth Daniela M, Jans David A

Abstract excerpt

Fundamental to eukaryotic cell function, nucleocytoplasmic transport can be regulated at many levels, including through modulation of the importin/exportin (Imp/Exp) nuclear transport machinery itself. Although Imps/Exps are overexpressed in a number of transformed cell lines and patient tumor tissues, the efficiency of nucleocytoplasmic transport in transformed cell types compared with nontransformed cells has...

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Identifiers

PMID: 22155563
DOI: 10.1096/fj.11-191585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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