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Article

Clinicopathological Characteristics of Papillary Thyroid Cancer in Children with Emphasis on Pubertal Status and Association with BRAFV600E Mutation.

Journal of clinical research in pediatric endocrinology - 1 Sept 2017

Poyrazoğlu Şükran, Bundak Rüveyde, Baş Firdevs, Yeğen Gülçin, Şanlı Yasemin, Darendeliler Feyza

Abstract excerpt

OBJECTIVE: Papillary thyroid cancer (PTC) may behave differently in prepubertal children as compared to pubertal children and adults. BRAF gene activating mutations may associate with PTC by creating aberrant activation. We aimed to evaluate the clinicopathological characteristics of PTC patients with emphasis on the pubertal status and also to investigate the association of BRAFV600E mutation with disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

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Share to Thyroid Cancer, Papillary

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Source

Open in PubMed Open full text

Identifiers

PMID: 28077340
DOI: 10.4274/jcrpe.3873
PMCID: PMC5596798

Genes

BRAF

Provenance

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