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Article

BRAF mutations are uncommon in papillary thyroid cancer of young patients.

Thyroid : official journal of the American Thyroid Association - 1 Apr 2005

Penko Karen, Livezey Jeffrey, Fenton Cydney, Patel Aneeta, Nicholson Diarmuid, Flora Michael, Oakley Kevin, Tuttle R Michael, Francis Gary

Abstract excerpt

Mortality is low for young patients (younger than 21 years) with papillary thyroid cancer (PTC), and different mutations might contribute to this. Previous studies detected ret/PTC rearrangements more frequently in PTC from children than adults, and recent reports describe a high incidence of BRAF T1796A transversion in adult PTC. However, BRAF mutations have not been adequately studied in PTC from young...

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Share to Adolescent
Share to Carcinoma, Papillary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Rearrangement

Share to Oncogene Proteins, Fusion

Share to Protein-Tyrosine Kinases

Share to Proto-Oncogene Proteins B-raf

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 15876153
DOI: 10.1089/thy.2005.15.320

Genes

BRAF

Variants

Provenance

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