Article
Mediators of diabetic neuropathy: is hyperglycemia the only culprit?
Current opinion in endocrinology, diabetes, and obesity - 1 Apr 2017
Grisold Anna, Callaghan Brian C, Feldman Eva L
Abstract excerpt
PURPOSE OF REVIEW: Diabetic peripheral neuropathy (DPN) is a disabling, highly prevalent complication of both type 1 and type 2 diabetes mellitus (T1DM and T2DM). Large clinical studies support the concept that, in addition to hyperglycemia, components of the metabolic syndrome (MetS) may underlie the pathogenesis of DPN, especially in T2DM. This review will present the evidence supporting the MetS and its...
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