Article
Criteria for creating and assessing mouse models of diabetic neuropathy.
Current drug targets - 1 Jan 2008
Sullivan Kelli A, Lentz Stephen I, Roberts John L, Feldman Eva L
Abstract excerpt
Diabetic neuropathy (DN) is a serious and debilitating complication of both type 1 and type 2 diabetes. Despite intense research efforts into multiple aspects of this complication, including both vascular and neuronal metabolic derangements, the only treatment remains maintenance of euglycemia. Basic research into the mechanisms responsible for DN relies on using the most appropriate animal model. The advent of...
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