Article
Improved survival for BRCA2-associated serous ovarian cancer compared with both BRCA-negative and BRCA1-associated serous ovarian cancer.
Cancer - 1 Aug 2012
Hyman David M, Zhou Qin, Iasonos Alexia, Grisham Rachel N, Arnold Angela G, Phillips Mary F, Bhatia Jasmine, Levine Douglas A, Aghajanian Carol, Offit Kenneth, Barakat Richard R, Spriggs David R, Kauff Noah D
Abstract excerpt
BACKGROUND: Multiple observational studies have suggested that breast cancer gene (BRCA)-associated ovarian cancers have improved survival compared with BRCA-negative ovarian cancers. However, most of those studies combined BRCA1 and BRCA2 patients or evaluated only BRCA1 patients. The objective of the current study was to examine whether BRCA1-associated and BRCA2-associated ovarian cancers were associated with...
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