Article
Germ cell-specific DNA methylation and genome diploidization in primitive vertebrates.
Epigenetics - 1 Dec 2011
Ma Shanshan, Huang Wanxu, Zhang Lei, Zhao Shufang, Tong Ying, Liu Zhenghua, Sun Lei, Chen Haiyan, Luo Chen
Abstract excerpt
Genomic imprinting in mammals causes certain genes to be expressed according to their parental origin and thereby prevents parthenogenesis. However, the evolutionary origin and significance of genomic imprinting remains unclear. Here, we study the methylation status of ntl, a developmentally decisive gene, in egg, sperm and early embryos at various developmental stages in bisexual diploid fish and unisexual...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.