Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epigenetic asymmetry in the mammalian zygote and early embryo: relationship to lineage commitment?

29 Aug 2003

Abstract excerpt

Epigenetic asymmetry between parental genomes and embryonic lineages exists at the earliest stages of mammalian development. The maternal genome in the zygote is highly methylated in both its DNA and its histones and most imprinted genes have maternal germline methylation imprints. The paternal genome is rapidly remodelled with protamine removal, addition of acetylated histones, and rapid demethylation of DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Genetic Syndromes and Imprinting
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14511488
DOI: 10.1098/rstb.2003.1326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epigenetic asymmetry in the mammalian zygote and early embryo: relationship to lineage commitment?PMID 14511488Read ↗

Epigenetic asymmetry in the zygote and mammalian developmentSemantic proximity Read ↗

Epigenetic dynamics during preimplantation developmentSemantic proximity Read ↗

Active Demethylation of Paternal Genome in Mammalian ZygotesSemantic proximity Read ↗

Embryo manipulation via assisted reproductive technology and epigenetic asymmetry in mammalian early development.Semantic proximity Read ↗

Epigenetic regulation of early human embryo developmentSemantic proximity Read ↗

New insights into mechanisms that regulate DNA methylation patterningSemantic proximity Read ↗

Epigenetic regulation in mammalian preimplantation embryo developmentSemantic proximity Read ↗

Insights into epigenetic patterns in mammalian early embryosSemantic proximity Read ↗

Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineagesSemantic proximity Read ↗

Revisiting trophectoderm-inner cell mass lineage segregation in the mammalian preimplantation embryoSemantic proximity Read ↗

Imprinting and the epigenetic asymmetry between parental genomes.Semantic proximity Read ↗

Developmental genome-wide DNA methylation asymmetry between mouse placenta and embryoSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.