Article
Multipotent stem/progenitor cells in the human foetal biliary tree.
Journal of hepatology - 1 Nov 2012
Semeraro Rossella, Carpino Guido, Cardinale Vincenzo, Onori Paolo, Gentile Raffaele, Cantafora Alfredo, Franchitto Antonio, Napoli Cristina, Anceschi Maurizio, Brunelli Roberto, Bosco Daniela, Torrice Alessia, Reid Lola, Gaudio Eugenio, Alvaro Domenico
Abstract excerpt
BACKGROUND & AIMS: Biliary tree, liver, and pancreas share a common embryological origin. We previously demonstrated the presence of stem/progenitor cells of endodermal origin in the adult human extrahepatic biliary tree. This study evaluated the human foetal biliary trees as sources of stem/progenitor cells of multiple endodermal-derived mature fates. METHODS: Human foetal intrahepatic and extrahepatic biliary...
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