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Article

Channeling dysglycemia: ion-channel variations perturbing glucose homeostasis.

Trends in endocrinology and metabolism: TEM - 1 Jan 2012

Denton Jerod Scott, Jacobson David Aaron

Abstract excerpt

Maintaining blood glucose homeostasis is a complex process that depends on pancreatic islet hormone secretion. Hormone secretion from islets is coupled to calcium entry which results from regenerative islet cell electrical activity. Therefore, the ionic mechanisms that regulate calcium entry into islet cells are crucial for maintaining normal glucose homeostasis. Genome-wide association studies (GWAS) have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22134088
DOI: 10.1016/j.tem.2011.09.004
PMCID: PMC3733341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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