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Article

Detection of BRAF mutations in patients with hairy cell leukemia and related lymphoproliferative disorders.

Haematologica - 1 May 2012

Blombery Piers A, Wong Stephen Q, Hewitt Chelsee A, Dobrovic Alexander, Maxwell Ellen L, Juneja Surender, Grigoriadis George, Westerman David A

Abstract excerpt

Hairy cell leukemia has been shown to be strongly associated with the BRAF V600E mutation. We screened 59 unenriched archived bone marrow aspirate and peripheral blood samples from 51 patients with hairy cell leukemia using high resolution melting analysis and confirmatory Sanger sequencing. The BRAF V600E mutation was detected in 38 samples (from 36 patients). The BRAF V600E mutation was detected in all samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22133769
DOI: 10.3324/haematol.2011.054874
PMCID: PMC3342983

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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