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Article

Epidermal growth factor receptor in breast carcinoma: association between gene copy number and mutations.

Diagnostic pathology - 2 Dec 2011

Lv Ning, Xie Xiaoming, Ge Qidong, Lin Suxia, Wang Xi, Kong Yanan, Shi Hongliu, Xie Xinhua, Wei Weidong

Abstract excerpt

BACKGROUND: The epidermal growth factor receptor (EGFR) is an available target of effective anti-EGFR therapy for human breast cancer. The aim of this study was to assess the presence of EGFR gene amplification and mutations in breast cancer and to analyze the association between the statuses of these two gene alterations. MATERIALS AND METHODS: EGFR gene amplification and mutations were investigated in...

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Identifiers

PMID: 22132735
DOI: 10.1186/1746-1596-6-118
PMCID: PMC3248849

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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