Article
AluYb8 insertion in the MUTYH gene and risk of early-onset breast and gastric cancers in the Chinese population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Zhu Ming, Chen Xiaoxiang, Zhang Huan, Xiao Nong, Zhu Changdong, He Qiong, Guo Wenwen, Cai Zhenming, Shen Hongbing, Wang Yaping
Abstract excerpt
BACKGROUND: A common polymorphism of the AluYb8 insertion in the MUTYH gene (AluYb8MUTYH), which led to the increase of oxidative DNA damage and acceleration of chronic diseases, was previously detected. Considering the relationship between carcinogenesis and oxidative stress, an investigation was held on whether the common variant of the MUTYH gene increases the risk for gastric and breast cancers. METHODS: The...
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