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Article

MSH2 rs2303425 Polymorphism is Associated with Early-Onset Breast Cancer in Taiwan.

Annals of surgical oncology - 1 Feb 2017

Hsieh Yi-Chen, Cho Er-Chieh, Tu Shih-Hsin, Wu Chih-Hsiung, Hung Chin-Sheng, Hsieh Mao-Chih, Su Chien-Tien, Liu Yun-Ru, Lee Chia-Hwa, Ho Yuan-Soon, Chiou Hung-Yi

Abstract excerpt

BACKGROUND: Accumulated evidence indicates that the incidence of early-onset breast cancer has rapidly increased in Taiwan and other Asian compared to Western countries. The mismatch repair (MMR) pathway might be one of the crucial mechanisms of predisposition to early breast cancer. In this study, we explored whether MMR gene polymorphisms contribute to the risk of breast cancer in young women. METHODS: This was...

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PMID: 26975740
DOI: 10.1245/s10434-016-5168-5

Genes

MSH2

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