Article
Prenatal smoking exposure and dopaminergic genotypes interact to cause a severe ADHD subtype.
Biological psychiatry - 15 Jun 2007
Neuman Rosalind J, Lobos Elizabeth, Reich Wendy, Henderson Cynthia A, Sun Ling-Wei, Todd Richard D
Abstract excerpt
BACKGROUND: In utero exposure to smoking and alcohol are common risk factors that have been associated with attention-deficit/hyperactivity disorder (ADHD) in human beings and animal models. Furthermore, molecular studies have focused on the association between ADHD and DNA polymorphisms in dopamine pathway-related genes. We examined the joint effects of genetic and prenatal substance exposures on DSM-IV and...
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