Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-195 Promotes Apoptosis in Mouse Podocytes via Enhanced Caspase Activity Driven by BCL2 Insufficiency

1 Jan 2011

Abstract excerpt

BACKGROUND: The apoptosis of podocytes is a characteristic event in diabetic nephropathy. The aim of this study was to investigate whether microRNAs (miRNAs) affect podocyte apoptosis in diabetic circumstances. METHODS: Diabetic nephropathy was induced in DBA/2 mice by intraperitoneal injections of streptozotocin, and the levels of proteinuria were measured with ELISA. Apoptosis-related miRNAs were screened in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Kidney Disease and Diabetes
Share to Genetic and Kidney Cyst Diseases
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22123611
DOI: 10.1159/000333809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-195 Promotes Apoptosis in Mouse Podocytes via Enhanced Caspase Activity Driven by BCL2 InsufficiencyPMID 22123611Read ↗

Abated microRNA-195 expression protected mesangial cells from apoptosis in early diabetic renal injury in miceSemantic proximity Read ↗

MiR-770-5p facilitates podocyte apoptosis and inflammation in diabetic nephropathy by targeting TIMP3Semantic proximity Read ↗

MicroRNAs in Podocyte Injury in Diabetic NephropathySemantic proximity Read ↗

Modulation of apolipoprotein L1-microRNA-193a axis prevents podocyte dedifferentiation in high-glucose milieu.Semantic proximity Read ↗

MicroRNA‑145‑5p attenuates high glucose‑induced apoptosis by targeting the Notch signaling pathway in podocytesSemantic proximity Read ↗

Metadherin facilitates podocyte apoptosis in diabetic nephropathySemantic proximity Read ↗

microRNA-20b contributes to high glucose-induced podocyte apoptosis by targeting SIRT7Semantic proximity Read ↗

Smad2-Dependent Downregulation of miR-30 Is Required for TGF-β-Induced Apoptosis in PodocytesSemantic proximity Read ↗

Regulation of podoplanin expression by microRNA-29b associates with its antiapoptotic effect in angiotensin II-induced injury of human podocytesSemantic proximity Read ↗

TNF-α-mediated podocyte injury via the apoptotic death receptor pathway in a mouse model of IgA nephropathySemantic proximity Read ↗

The long noncoding RNA LOC105374325 causes podocyte injury in individuals with focal segmental glomerulosclerosisSemantic proximity Read ↗

Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.