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Article

Abated microRNA-195 expression protected mesangial cells from apoptosis in early diabetic renal injury in mice

4 Oct 2011

Abstract excerpt

BACKGROUND: MicroRNAs are a class of highly conserved, small, noncoding RNAs that tailor gene expression mainly at the posttranscriptional level. The aim of the present study was to investigate the renal expression profiles of microRNAs and their potential involvement in early diabetic nephropathy. METHODS: Diabetic models were induced with streptozotocin in DBA/2 mice. MicroRNAs were detected by microarray and...

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PMID: 21983986
DOI: 10.5301/jn.5000034

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