Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA‑145‑5p attenuates high glucose‑induced apoptosis by targeting the Notch signaling pathway in podocytes

7 Jan 2020

Abstract excerpt

MicroRNAs (miRNAs/miRs) are considered to serve essential roles in podocyte apoptosis, and to be critical in the development of diabetic nephropathy (DN). Activation of the Notch signaling pathway has been demonstrated to serve an important role in DN development; however, its regulatory mechanisms are not fully understood. The present study used a high glucose (HG)‑induced in vitro apoptosis model using mouse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Kruppel-like factors research
Share to MicroRNA in disease regulation
Share to Renal Diseases and Glomerulopathies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32104249
DOI: 10.3892/etm.2020.8427

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA‑145‑5p attenuates high glucose‑induced apoptosis by targeting the Notch signaling pathway in podocytesPMID 32104249Read ↗

microRNA-20b contributes to high glucose-induced podocyte apoptosis by targeting SIRT7Semantic proximity Read ↗

MiR-770-5p facilitates podocyte apoptosis and inflammation in diabetic nephropathy by targeting TIMP3Semantic proximity Read ↗

Metadherin facilitates podocyte apoptosis in diabetic nephropathySemantic proximity Read ↗

MicroRNA-195 Promotes Apoptosis in Mouse Podocytes via Enhanced Caspase Activity Driven by BCL2 InsufficiencySemantic proximity Read ↗

MicroRNA regulation of the proliferation and apoptosis of Leydig cells in diabetesSemantic proximity Read ↗

Dysregulation of lncRNAs GM5524 and GM15645 involved in high‑glucose‑induced podocyte apoptosis and autophagy in diabetic nephropathySemantic proximity Read ↗

Abated microRNA-195 expression protected mesangial cells from apoptosis in early diabetic renal injury in miceSemantic proximity Read ↗

miR-145 improves metabolic inflammatory disease through multiple pathwaysSemantic proximity Read ↗

The Role of MicroRNA-155 in Glomerular Endothelial Cell Injury of Diabetic NephropathySemantic proximity Read ↗

Long noncoding RNA SNHG5 promotes podocyte injury via the microRNA-26a-5p/TRPC6 pathway in diabetic nephropathySemantic proximity Read ↗

GADD45B mediates podocyte injury in zebrafish by activating the ROS-GADD45B-p38 pathwaySemantic proximity Read ↗

Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.