Article
A genetic locus for paranoia.
Biology letters - 1 Jan 2018
Crespi Bernard, Read Silven, Salminen Iiro, Hurd Peter
Abstract excerpt
The psychological effects of brain-expressed imprinted genes in humans are virtually unknown. Prader-Willi syndrome (PWS) is a neurogenetic condition mediated by genomic imprinting, which involves high rates of psychosis characterized by hallucinations and paranoia, as well as autism. Altered expression of two brain-expressed imprinted genes, MAGEL2 and NDN, mediates a suite of PWS-related phenotypes, including...
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