Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Novel cell lines established from pediatric brain tumors.

Journal of neuro-oncology - 1 Apr 2012

Xu Jingying, Erdreich-Epstein Anat, Gonzalez-Gomez Ignacio, Melendez Elizabeth Y, Smbatyan Goar, Moats Rex A, Rosol Michael, Biegel Jaclyn A, Reynolds C Patrick

Abstract excerpt

The paucity of cell culture models for childhood brain tumors prompted us to establish pediatric cell lines for use in biological experiments and preclinical developmental therapeutic studies. Three cell lines were established, CHLA-200 (GBM), CHLA-259 (anaplastic medulloblastoma) and CHLA-266 (atypical teratoid rhabdoid tumor, AT/RT). Consistent with an AT/RT origin, CHLA-266 lacked INI1 expression and had...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glioma

Share to Magnetic Resonance Imaging

Share to Oncogenes

Share to Pediatrics

Share to Tumor Cells, Cultured

Share to Xenograft Model Antitumor Assays

Source

Open in PubMed Open full text

Identifiers

PMID: 22120608
DOI: 10.1007/s11060-011-0756-5
PMCID: PMC3379550

Genes

MYC
MYCN
GFAP
PGP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Novel cell lines established from pediatric brain tumors.PMID 22120608Read ↗

Pediatric brain tumor cell lines.Semantic proximity Read ↗

Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunitiesSemantic proximity Read ↗

Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.Semantic proximity Read ↗

Pioneering models of pediatric brain tumors.Semantic proximity Read ↗

Pediatric low-grade gliomas: molecular characterization of patient-derived cellular models.Semantic proximity Read ↗

Wilms tumor primary cultures capture phenotypic heterogeneity and facilitate preclinical screeningSemantic proximity Read ↗

3D patient-derived tumor models to recapitulate pediatric brain tumors In VitroSemantic proximity Read ↗

Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor.Semantic proximity Read ↗

Limitations of current in vitro models for testing the clinical potential of epigenetic inhibitors for treatment of pediatric ependymomaSemantic proximity Read ↗

Characterization of five new cell lines derived from human primitive neuroectodermal tumors of the central nervous system.Semantic proximity Read ↗

c-Myc Overexpression Causes Anaplasia in MedulloblastomaSemantic proximity Read ↗

Genetic alterations and in vivo tumorigenicity of neurospheres derived from an adult glioblastoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.