Article
Adaptive evolution and fixation of drug-resistant Plasmodium falciparum genotypes in pregnancy-associated malaria: 9-year results from the QuEERPAM study.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2012
Taylor Steve M, Antonia Alejandro, Feng Gaoqian, Mwapasa Victor, Chaluluka Ebbie, Molyneux Malcolm, ter Kuile Feiko O, Rogerson Stephen J, Meshnick Steven R
Abstract excerpt
Sulfadoxine-pyrimethamine (SP) has been widely deployed in Africa for malaria control and molecular evidence of parasite drug-resistance is prevalent. However, the temporal effects on the selection of Plasmodium falciparum are not well understood. We conducted a retrospective serial cross-sectional study between 1997 and 2006 to investigate changes in drug-resistant malaria among pregnant women delivering at a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
