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Article

After GWAS: mice to the rescue?

Current opinion in immunology - 1 Oct 2012

Ermann Joerg, Glimcher Laurie H

Abstract excerpt

The genetic basis of human autoimmune diseases remains incompletely understood, despite significant progress from genome-wide association studies (GWAS). In this review we outline how studies in mice may help filling these knowledge gaps. Forward genetic approaches including mutagenesis screens and quantitative trait locus (QTL) mapping studies can identify candidate genes for in depth analysis in human patient...

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Identifiers

PMID: 23031443
DOI: 10.1016/j.coi.2012.09.005
PMCID: PMC3631559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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