Article
Modulation of growth and differentiation in normal human keratinocytes by transforming growth factor‐β
1 Oct 1990
Abstract excerpt
The effect of transforming growth factor-type beta 1(TGF-beta) on the growth and differentiation of normal human skin keratinocytes cultured in serum-free medium was investigated. TGF-beta markedly inhibited the growth of keratinocytes at the concentrations greater than 2 ng/ml under low Ca2+ conditions (0.1 mM). Growth inhibition was accompanied by changes in cell functions related to proliferation. Remarkable...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
