Article
Genetic response to an environmental pathogenic agent: HLA-DQ and onchocerciasis in northwestern Ecuador.
Tissue antigens - 1 Feb 2012
De Angelis F, Garzoli A, Battistini A, Iorio A, De Stefano G F
Abstract excerpt
The aim of this study is to explore human leukocyte antigen (HLA)-DQ variability in two populations (Cayapas Amerindians and Afro-Ecuadorians) who live near one another along the Cayapa River and who are exposed to the same environmental stresses, such as infection by Onchocerca volvulus. HLA-DQA1 and HLA-DQB1 of 149 unrelated individuals (74 Cayapas and 75 Afro-Ecuadorians) have been analyzed. HLA...
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