Genetic diversity of the HLA system in human populations from the Sierra (Andean), Oriente (Amazonian) and Costa (Coastal) regions of Ecuador.

doi:10.1016/j.humimm.2018.06.004

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Article

Genetic diversity of the HLA system in human populations from the Sierra (Andean), Oriente (Amazonian) and Costa (Coastal) regions of Ecuador.

Human immunology - 1 Sept 2018

Galarza Juan M, Barquera Rodrigo, Álvarez Ana M Tito, Hernández Zaragoza Diana I, Sevilla Gabriela Peralta, Tamayo Andrea, Pérez Mariel, Dávila David, Birnberg Lotty, Alonzo Víctor Acuña, Krause Johannes, Grijalva Marcelo

Abstract excerpt

We studied HLA class I (HLA-A, -B) and class II (HLA-DRB1, -DQB1) alleles by PCR-SSP based typing in a total of 1101 Ecuadorian individuals from three regions of the country, the Coastal region, the Andean region, and the Amazonian region, to obtain information regarding allelic and haplotypic frequencies and their linkage disequilibrium. We find that the most frequent HLA haplotypes with significant linkage...

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PMID: 29908213
DOI: 10.1016/j.humimm.2018.06.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.