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Article

FOXA1: a transcription factor with parallel functions in development and cancer

31 Oct 2011

Abstract excerpt

When aberrant, factors critical for organ morphogenesis are also commonly involved in disease progression. FOXA1 (forkhead box A1), also known as HNF3α (hepatocyte nuclear factor 3α), is required for postnatal survival due to its essential role in controlling pancreatic and renal function. In addition to regulating a variety of tissues during embryogenesis and early life, rescue experiments have revealed a...

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PMID: 22115363
DOI: 10.1042/bsr20110046

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