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Article

FOXA1 as a therapeutic target for breast cancer

20 Mar 2007

Abstract excerpt

Gene expression profiling studies have classified breast cancer into five intrinsic subtypes with distinct prognostic significance: luminal type A, luminal type B, normal-like, HER-2-positive and basal type. These studies have also uncovered novel diagnostic markers and molecular targets. FOXA1, a winged-helix transcription factor belonging to the forkhead family, is one among them as it is expressed...

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PMID: 17373880
DOI: 10.1517/14728222.11.4.507

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