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Article

CMV reactivation initiates long-term expansion and differentiation of the NK cell repertoire

1 Dec 2022

Abstract excerpt

Introduction: NK cells play an important role in suppression of viral replication and are critical for effective control of persistent infections such as herpesviruses. Cytomegalovirus infection is associated with expansion of 'adaptive-memory' NK cells with a characteristic CD56dimCD16bright NKG2C+ phenotype but the mechanisms by which this population is maintained remain uncertain. Methods: We studied NK cell...

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PMID: 36531994
DOI: 10.3389/fimmu.2022.935949

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